Deprecated: Unparenthesized `a ? b : c ? d : e` is deprecated. Use either `(a ? b : c) ? d : e` or `a ? b : (c ? d : e)` in /home/u504777/ on line 930

Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /home/u504777/ on line 646

Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /home/u504777/ on line 663
Useful information « Histograft LLC
→    Training webinars are now on record (RU) free

The results of the research and development carried out were published by the company’s employees in collaboration with partners, and reported at Russian and international scientific conferences. The main publications are listed below. Articles published by publishers in the full-text version are freely available for download.

Оngoing clinical trials (post-marketing)


«Genes and Cells» (the old name «Cell Transplantology and Tissue Engineering») is a peer-reviewed scientific and practical journal recommended by the Higher Attestation Commission of the Ministry of Education and Science of the Russian Federation for publishing the main materials of dissertation research.


Registration certificate for a medical device (RU)

Instructions for the use of a medical device (RU)

Scientific articles

Bringing a Gene-Activated Bone Substitute Into Clinical Practice: From Bench to Bedside

The Few Who Made It: Commercially and Clinically Successful Innovative Bone Grafts

3D Printed Gene-activated Octacalcium Phosphate Implants for Large Bone Defects Engineering

Systematic review of the preclinical technology readiness of orthopaedic gene therapy and outlook for clinical translation

World’s First Clinical Case of Gene-Activated Bone Substitute Application
Bozo I.Y., Deev R.V., Drobyshev A.Y., Isaev A.A., Eremin I.I.
Case Rep Dent. 2016; 2016:8648949. Epub 2016 Nov 7. PMID: 27891264 Free PMC Article

Regenerative Medicine and Plastic Surgery.Ordinary and Activated Bone Substitutes
Bozo, Ilya Y., (et al.)
DOI 978-3-030-19962-3_14, © 2019

Ordinary and activated bone grafts: applied classification and the main features
Deev R.V., Drobyshev A.Y., Bozo I.Y., Isaev A.A.
Biomed Res Int. 2015; 2015: 365050. DOI: 10.1155/2015/365050

3D Printing of Octacalcium Phosphate Bone Substitutes
Komlev V.S., Popov V.K., Mironov A.V., Fedotov A.Y., Teterina A.Y., Smirnov I.V., Bozo I.Y., Rybko V.A., Deev R.V.
Front. Bioeng. Biotechnol. 2015; 3:81. DOI: 10.3389/fbioe.2015.00081

Bioceramics composed of octacalcium phosphate demonstrate enhanced biological behavior
Komlev V.S., Barinov S.M., Bozo I.I., Deev R.V., Eremin I.I., FedotovA.Yu., Gurin A.N., Khromova N.V., Kopnin P.В., Kuvshinova E.A., Mamonov V.E., Rybko V.A., Sergeeva N.S., TeterinaA.Yu., Zorin V.L.
ACS Appl. Mater. Interfaces, 2014; 6(19): 16610-20. DOI: 10.1021/am502583p